Studies on some novel ionexchange resin supported reagents in organic synthesis

Abstract

PART-A Chapter A.I Page no. 36 Solid phase reduction of oxazolones using BER-Ni2B : A simple synthesis of N-benzoylphenylalanines Borohydride exchange resin (BER)-Ni2B is successfully used as a reagent for the solid phase reduction of the C-4 exocyclic double bond of oxazolones to give the N-benzoylphenylalanines and hence the corresponding amino acids. Chapter A.II Page no. 73 Solid phase selective reduction of olefinic bond in a,B-unsaturated ketones using BER-Ni2B quotSolid Phasequot selective reduction of olefinic bond of chalcones and related enones using BER-Ni2B system is described. Chapter A.III Page no. 98 Solid Phase reduction of resin immobolized aryl diazonium ion by aqueous sodium borohydride : A simple synthesis of arylhydrazines. The preparation of arlyhydrazines by solid phase reduction of resin immobilized arydiazonium ions using aqueous sodium borohydride is described. PART-B Chapter B.I Page no. 115 Solid phase oxidation of aromatic aldehydes to corresponding carboxylic acids using Bromate Exchange Resin Synthetic importance of bromate exchange resin in carrying out quotSolid Phasequot oxidation of aromatic aldehydes giving the corresponding carboxylic acids is emphasized. Chapter B.II Page no. 127 solid Phase oxidation of alcohols and benzyl halides to corresponding carbonyls using Bromate Exchange Resin Utilization of bromate exchange resin for oxidation of alcohols and benzyl halide to the corresponding carbonyl compounds in biphasic conditions is described. Chapter B.III Page no. 142 Solid phase bromination of olefinic bonds and electrophilic (bromination) substitution in aromatic substrates Immobilization of tribromide ion onto ion-exchange resin support and subsequent reaction with the substrates to give the corresponding brominated products in solid phase is emphasized.