DEVELOPMENT AND PRECLINICAL EVALUATION OF SOLID ORAL DOSAGE FORM USING A NATURAL BIOENHANCING AGENT FOR RHEUMATOID ARTHRITIS

Abstract

Traditional aboriginal knowledge of plants is responsible for most of the medicine and food used in modern society Herbs have been used throughout time as food and as a primary tool for maintaining health and aiding in the recovery of disease About 80 percentage of the world population use plant based medicines and about one third of the world countries depend on herbal medicines Arthritis is leading cause of disability in adults all over the world limiting day to day activities for billion of people WHO reports that 1 percentage of the world population is affected by arthritis from Greek arthro joint and itis inflammation It is a joint disorder featuring inflammation Arthritis is frequently accompanied by joint pain which is referred to as arthralgia There are many types of arthritis which range from those related to wear and tear of cartilage such as osteoarthritis to those associated with inflammation resulting from an overactive immune system such as rheumatoid arthritis The causes of arthritis depend on the form of arthritis Some of the leading causes include injury leading to osteoarthritis metabolic abnormalities such as gout and pseudogout hereditary factors direct and indirect effect of infections and autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. newline