correlation study of vitamin d status with various disease conditions

Abstract

Background: The aim and objectives of this study was to evaluate the Vitamin D status and its association with various disease conditions. Understanding this correlation is essential to gain insights into the prevalence of Vitamin D deficiency in relation to Diabetes, Anaemia, Cholesterol, Thyroid, Testosterone and PSA among the people of this region. newlineMethods: A retrospective analysis was conducted using data from subjects (gt18 years) who underwent laboratory investigation includes the estimation of Vitamin D3 and with it estimation of HbA1c, Iron, Haemoglobin, Lipid parameters, Thyroid parameters, Testosterone, PSA at various study sites across north Gujarat, India. The primary variables studied were the proportions of subjects with different Vitamin D (25(OH)D) total levels, classified as deficiency (lt30 ng/ml) or Sufficiency (30-100 ng/ml). newlineResults: The analysis included data from 1109 subjects with a mean age of 46.97 (±13.39) years. Among them, 941 (84.9%) had Vitamin D levels below 30 ng/ml, with a slightly higher prevalence in males (85.78%) compared to females (83.81%). The age group with the highest incidence of vitamin D levels below 30 ng/ml was 21 40 years (87.17%), followed by gt 60 years (86.34%), and 41 60 years (82.57%). In Diabetes group, 666 (60.05%) subjects were Diabetic, while 443 (39.95%) were Non-Diabetic. Regarding Iron deficient anaemia group, [290 (26.1%) {M-140(23.97%)} {F-150(28.57%)}] subjects were Iron deficient anaemic, while [819 (73.9%) {M-444(76.03%)} {F-375(71.43%)}] had normal Iron levels. From Anaemic (Hb) subjects group, [255 (22.99%) {M-99(16.95%)} {F-156(29.71%)}] were Anaemic (low Hb), while [854 (77.01%) {M-485(83.05%)} {F-369(70.29%)}] were having normal value of Haemoglobin. Further, in Lipid disorder subject, 623 (56.18%) had abnormal levels, while 486(43.82%) had normal levels. Regarding Thyroid profiles, 1000 (90.2%) subjects had levels within the normal range, while 109 (9.8%) had abnormallity. In Testosterone group, 620 (55.9%) subjects had levels within the nor