Study Of Sperm Motility And Morphology In Smokers

Abstract

Background: Smoking has been linked to a myriad of adverse health outcomes, newlineincluding cardiovascular disease, respiratory disease, and cancer of the lungs, bladder, newlinecervix, esophagus, kidney, pancreas, and stomach. More recently, researchers have newlinebegun to explore the relationship between cigarette smoking and reproductive health. newlineObjective: To assess the impact of cigarette smoking on sperm Motility and newlineMorphology. newlineMethods: The present single-centric prospective case-control study was conducted on newline300 subjects. Male partners of couples complaining of impaired fertility presenting to newlineObstetrics and Gynaecology and ivf OPD were included. Sperm samples were newlinecollected from men smokers and non-smokers by masturbation in sterile container newlineafter sexual abstinence of 3-5 days at NIMS Medical college and Hospital and Evaa newlineHospital Jaipur. Semen volume was measured. Routine semen analysis was carried newlineout by light microscope. The Motility and Morphology of spermatozoa were assessed newlineaccording to WHO criteria (WHO 2010). newlineResults: Of the total 300 subjects 150 were cases and 150 were controls. Mean age of newlinethe cases was 30.51±7.44 years and mean age of the controls was 32.15±7.26 years. newline57 (38.0%) cases had children and 121 (80.7%) controls had children. Distribution of newlinethe studied patients who had children was found to be significant among both the newlinegroups (plt0.05). Majority 63 (42.0%) patients of case group smoke more than 20 newlinecigarettes per day followed by 46 (30.7%) patients who smoke 10-20 cigarettes and newlineleast 41 (27.3%) patients smoke less than 10 cigarettes per day. There was a newlinestatistically significant association found between duration of Smoking with cases newlinehaving children among both the groups (plt0.05). A statistically significant association newlinewas found between distribution of Motility and Morphology of the study population newlineof both the groups (plt0.05). The associations between No. of Cigarette Smoking/day newlinewith Motility and Morphological Abnormalities were found significantly correlated newline(plt0.05).Pear