Biochemical Changes Between Rapid And Conventional Orthodontic Tooth Movement A Comparative Study

Abstract

Background: Accelerated orthodontics has revolutionized the field of orthodontic newlinetreatment. Reducing the overall treatment time remains the prime concern of an newlineorthodontist. A good accelerating technique should be affordable, repeatable, practical, newlineefficient, and should not have any side effects on periodontium including root and newlinealveolar bone. In the era of technology, many advances are made and newer techniques newlinefor accelerating orthodontic treatment have been introduced in order to reduce the length newlineof treatment with minimal risk of side effects. The study was under taken to compare the newlinebiochemical changes in rapid and conventional orthodontic tooth movement. Material newlineand Method: A split mouth study was conducted on thirty patients undergoing fixed newlineorthodontic treatment requiring all four first premolar extraction. The extraction space newlineclosure was carried out with micro osteoperforations on the distal aspect along with newlineorthodontic force application on the right side and conventional orthodontic tooth newlinemovement on left side. GCF was collected before the micro osteoperforation (T0), at newlineday 3 (T1), at day 7 (T2) and at 4 weeks (T3) of initiating canine retraction from the newlinedistal gingival crevice of maxillary canine from both the sides of the arch. Quantitative newlineanalysis of IL-1 and Osteocalcin in GCF sample were assessed. The optical density of newlinesamples was calculated using a fully automated enzyme linked immunosorbent assay newlinereader. newlineResult: The level of Interleukin-1 and Osteocalcin were always higher at the micro newlineosteoperforation site compared to that of baseline values. Conclusion: A gradual newlineincrease in the levels of IL-1 and Osteocalcin was in both conventional and micro newlineosteoperforation side but statistically significant elevated levels of IL-1 and Osteocalcin newlinewas seen in micro osteoperforation side compared to conventional side. newlineKeywords: Orthodontic treatment, Tooth movement, Accelerated orthodontic newline