Electrochemical synthesis of carbocyclic and heterocyclic motifs

Abstract

Electro-organic synthesis has gained widespread attention due to the advantages such as green catalyst, atom economy, good selectivity and excellent yields. The use of newlinetailor-made modified electrodes helps in refining the electronic and surface properties which could be harnessed for synthesis of important heterocyclic and carbocyclic motifs. The fabrication of modified electrode is done by employing a carbon fiber paper substrate as the base followed by electropolymerization of a desired monomer. The functional group in the monomer is utilized for covalently immobilizing the desired catalyst such as enzyme, organometallic, transition-metal and organocatalyst over the electrode. The developed electrocatalyst is employed in the electrochemical synthesis of heterocyclic and carbocyclic motifs. The electrochemical characterization studies for the electrodes were determined using electrochemical active surface area, electrochemical impedance spectroscopy and electron transfer kinetics studies. The surface morphology of the fabricated electrode was differentiated in contrast to the other electrode by utilizing Scanning electron microscopy (SEM) and Optical Profilometry (OP). The other characterization of the electrode includes X-ray photoelectron spectroscopy (XPS), Fourier Transform Infrared (FT-IR) analysis for the newlinestructural confirmations. The fabricated modified electrode was then employed for the newlineelectrochemical organic transformation by carrying out several optimization reactions. newlineThe screening studies was carried out by employing different supporting electrolyte, newlinesolvents and electrochemical studies. The completion of the electrochemical organic newlinesynthesis was observed by Thin-layer chromatography (TLC) and desired product was newlineisolated either using column chromatography or just by solvent evaporation after newlineworkup.