A Comparative Clinical Study on the effect of Anupana Bheda Trivrutta Churna Nitya Virechana in Yakruta Vikara Liver Disorders with special reference to Abnormal Liver Function Tests

Abstract

newline Abstract: newlineBackground: liver is a key organ, which performs many functions related to metabolism, energy storage, and detoxification of waste from the body. It helps to digest food, convert it to energy and store the energy until its need. Along with this, it helps to filter toxic substances out of bloodstream. Liver disease is a wide-ranging term that refers to any condition affecting liver. These conditions may develop for different reasons, but can all damage to liver and impacts its functions. In the Ayurvedic classics, Yakut (Liver) is a Moola Sthana of Ratktavaha Strotas. So, the liver diseases come under the disorders of Raktavaha Strotas. In the relation of treatment part of Raktavaha Strotas Vikara, Virechana Karma has got prime importance. Aim and Objective: This study was designed to study the effect of Trivrutta Churna Nitya Virechana with difference of Anupana (Sharkara and Goghruta) in Yakrut Vikara (Liver Diseases) with abnormal liver function test. Methodology: In present comparative clinical trial, 80 patients of liver disease will be divided into 2 groups (40 in each). In group A - Trivrutta Churna (in the form of Nitya Virechana) 7 gms along with Anupana Sharkhara 14 gms will be administered once in the morning for a period of 3 weeks; and in Group B - Trivrutta Churna (in the form of Nitya Virechana) 7 gms along with Anupana Goghruta 14 gms will be administered once in the morning for a period of 3 weeks. These subjects will be followed further for another 3 weeks after treatment period. Assessments will be recorded on 0, 11th 21st and 42nd day. Results: The outcomes will be evaluated on the objective and subjective parameters. Conclusion: Effect of Trivrut Churna with Sharkara (sugar) showed that the effect of therapy is seen on subjective parameters but statistically no significant changes are seen on objective parameters. Effect of Trivrut Churna with Goghruta (Fat) showed statistically significant difference on bilirubin. In comparative study, no significant difference was obser