Standard Control Clinical Trial of Various Kalpana of Yavani on Udavartini Yonivyapad with Special Reference to Primary Dysmenorrhoea

Abstract

Introduction: Dysmenorrhoea is the most common aliment in female of reproductive newlineage group which often tend to hamper day to day life during menstrual phase. Approximate 75% of adolescent and 50% of adult woman face this issue every month. Majority of the cases fall under the primary dysmenorrhea where any pelvic pathology is not present. Dysmenorrhoea can be correlated with Udavartini Yonivyapad symptomatically. Present study was intended to provide effective remedy for immediate relief in symptoms of primary dysmenorrhea. Aims and Objectives- Conceptual study of Udavartini Yonivyapad and dysmenorrhoea. To standardize dose of Yavani Arka Bhavita Churna. To evaluate individual effect of Yavani Churna, Yavani Arka and Yavani Arka Bhavita Churna in Udavartini Yonivyapad. To compare the efficacy of Yavani Churna, Yavani Arka and Yavani Arka Bhavita Churna with standard drug in Udavartini Yonivyapad. Methodology After the physicochemical analysis and safety profile evaluation a randomized clinical trial was conducted where 216 patient of reproductive age group were selected and categorized in 4 groups 54 patient each. Among the 4 groups 3 groups were trial group and 1 was control group. The subjects of trial group were administered with Yavani Churna -Group A, Yavani Arka- Group B and Yavani Arka Bhavita Churna- Group C orally. All subjects of control group D were newlineadministered with Mefenamic acid. All intervention was given for 3 days during newlinemenstruation for 3 cycles. Assessment parameters were evaluated statistically. newlineResults: Statistical analysis of the parameters indicated significant result on VAS, nature of pain, duration of pain, nausea, vomiting, anorexia headache, breast newlinetenderness in trial group with better result in group C whereas in trial group D newlinesignificant difference found with all parameters except nausea, vomiting, anorexia newlineand breast pain.