Synthesis characterization and applications of peptide functionalized metallic nanomaterials

Abstract

The thesis is devoted for the synthesis of metallic nanomaterials which are among the most widely studied functional materials for their diverse applications in biosensing, electronics and biomedicine field. The synthesis for metallic nanomaterials has been carried out using peptides, protein and organic ligands as templates. Apart from conventional synthesis route, the novel methodology based upon microwave has been proposed for size tunable synthesis of gold nanomaterial from ultrasmall fluorescent gold nanoclusters to plasmonic nanoparticles in rapid (3 min), one pot and facile manner. All the synthesized nanomaterials were in-dept characterized using numerous high-end analytical techniques to understand all the structural aspect. The applicability of the synthesized nanomaterials has been explored for the sensing of pesticides, biologically relevant enzyme and for antimicrobial activity of metallic nanoclusters. Also, self-assembled micro/nanostructured of diphenylalanine peptide and its structural analogs were fabricated in order to understand the role of structural integrity during quantum confinement effect. Therefore, the present thesis will be useful in widen the horizon towards the development of metallic nanomaterial using simplistic approach and their applications in diverse fields. newline