Shodhganga : a reservoir of Indian theses @ INFLIBNET
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/562867
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.coverage.spatial | Biochemistry | |
| dc.date.accessioned | 2024-05-06T04:56:45Z | - |
| dc.date.available | 2024-05-06T04:56:45Z | - |
| dc.identifier.uri | http://hdl.handle.net/10603/562867 | - |
| dc.description.abstract | The present study was carried out in liver to elucidate the epigenetic, biochemical and molecular mechanism of folate modulation with ageing on folate transporters, and promoter methylation of tumor suppressor and proto-oncogenes in an in-vivo model of folate deficiency and supplementation, to understand the intricate mechanism between age and DNA methylation. The folate modulation was also observed in an invitro model of liver cancer cell lines to understand the role of mTOR associated with autophagy. newline | |
| dc.format.extent | IV, 171p. | |
| dc.language | English | |
| dc.relation | - | |
| dc.rights | university | |
| dc.title | Cellular and molecular evaluation of aberrant hepatic DNA methylation by folate modulation and ageing | |
| dc.title.alternative | ||
| dc.creator.researcher | Najar, Rauf Ahmad | |
| dc.subject.keyword | Autophagy | |
| dc.subject.keyword | Cancer physiology | |
| dc.subject.keyword | Folate deficiency | |
| dc.subject.keyword | Folic acid | |
| dc.subject.keyword | Liver tissue folate levels | |
| dc.subject.keyword | Serum folate levels | |
| dc.description.note | Bibliography 137-171p. | |
| dc.contributor.guide | Dar, Abid Hamid | |
| dc.publisher.place | Chandigarh | |
| dc.publisher.university | Panjab University | |
| dc.publisher.institution | Department of Biochemistry | |
| dc.date.registered | 2012 | |
| dc.date.completed | 2017 | |
| dc.date.awarded | 2018 | |
| dc.format.dimensions | - | |
| dc.format.accompanyingmaterial | CD | |
| dc.source.university | University | |
| dc.type.degree | Ph.D. | |
| Appears in Departments: | Department of Biochemistry | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01_title.pdf | Attached File | 50.82 kB | Adobe PDF | View/Open |
| 02_prelim pages.pdf | 174.57 kB | Adobe PDF | View/Open | |
| 03_chapter1.pdf | 152.42 kB | Adobe PDF | View/Open | |
| 04_chapter2.pdf | 1.78 MB | Adobe PDF | View/Open | |
| 05_chapter3.pdf | 390.76 kB | Adobe PDF | View/Open | |
| 06_chaoter4.pdf | 3.69 MB | Adobe PDF | View/Open | |
| 07_chapter5.pdf | 906.11 kB | Adobe PDF | View/Open | |
| 08_chapter6.pdf | 159.28 kB | Adobe PDF | View/Open | |
| 09_annexure.pdf | 464.18 kB | Adobe PDF | View/Open | |
| 80_recommendation.pdf | 199.58 kB | Adobe PDF | View/Open |
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