Two arm randomized open labeled standard controlled prospective clinical study to evaluate the efficacy of herbal and synthetic dentifrices in dentinal hyper sensitivity

Abstract

newline Dentin hypersensitivity could be defined as a short, sharp pain arising from exposed dentin in newlineresponse to stimuli typically thermal, evaporative, tactile, osmotic, or chemical and which newlinecannot be ascribed to any other form of dental defect or pathology. In Ayurveda Dentinal newlineHypersensitivity can be compared with Dantaharsha. When teeth are sensitized to newlinecold/breeze, hot, dry and sour eatables and have pain and shaky feeling, the condition is newlinecalled Dantaharsha . Toothpastes are the most widely used dentifrices for delivering overthe- newlinecounter desensitizing agents.The aim study was to evaluate the effect of Herbal newlinedentifrices in Dentinal hypersensitivity. The objective of this study was to prepare palatable newlineformulation of Herbal Dentifrices to maintain oral health and prevent oral pathologies newlineMaterials and Methods: newlineIn this open-labelled, randomized,controlled study, 60 assenting patients between 18-40 years newlineof age were enrolled and randomized into trial and control groups, after obtaining EC newlineapproval and informed consent. Those in the trial group received Herbal dentifrices, control newlinegroup participants received Synthetic dentifrices. Herbal and synthetic dentifrices given to newlineapply twice a day for 3 wks. Follow up was taken after second week and third week.The newlineduration of treatment was of 21 days. Dentifrice was prepared under all hygienic conditions newlineand safety precautions in GMP certified pharmacy. Effect in Dentinal hypersensitivity was newlineassessed by scored using VAS on air stimulus and cold-water stimulus and Air Blast newlineStimulation Schiff Cold Air Sensitivity Scale.Appropriate statistical tests applied to the data newlineto obtain results newlineResults: On analysis of data generated through clinical assessment, improvement was seen newlinein dentinal hypersensitivity in both the groups. Though synthetic dentifrice showed better newlineresults than the herbal one, the trial drug exhibited a promising output in the study. newlineStatistically Group B shows better results in the median Hypersensitivity score on VAS and newlineAir blast stimulati