Significance Of Hormone Receptor Activity And Proliferative Activity In Normal Hyperplastic And Neoplastic Endometrium In Correlation With Metaplastic Changes And Clinical Parameters

Abstract

To identify the role of hormone receptor activity - estrogen newlinereceptor (ER), progesterone receptor (PR), and proliferative activity newline- Ki67 immunomarkers in normal, hyperplastic, and endometrial newlinecarcinomas and correlation with metaplastic changes and clinical newlineparameters. newlineOBJECTIVES newline To study the spectrum of histomorphological lesions of newlineendometrium. newline To analyze the expression of hormone receptor markers such newlineas ER, PR in normal, hyperplastic, and endometrial newlinecarcinoma. newline To analyze the expression of proliferative index marker newline(Ki67) in normal, hyperplastic, and endometrial carcinoma. newline To corelate above mentioned findings with clinical parameters newlinemetaplastic changes newline