Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/530066
Title: | a retrospective study of the clinicopathological profile of colorectal carcinoma and its correlation with markers of microsatellite instability at a tertiary care center |
Researcher: | Neha Agarwal |
Guide(s): | Ganthimathy Sekhar |
Keywords: | Clinical Medicine Clinical Pre Clinical and Health Pathology |
University: | Saveetha University |
Completed Date: | 2023 |
Abstract: | newlineTo study the immunohistochemical expression of markers of newlinemicrosatellite instability (MSI) in colorectal cancers and correlate newlinethe findings with clinicopathological factors. newlineOBJECTIVES newline1. To tabulate the age and gender characteristic of cases of newlinesurgically resected specimens of colorectal carcinoma newlinereceived at our institute . newline2. To list out the gross features, site in the colon and laterality newlineof the colorectal carcinoma cases. newline3. To tabulate the histological features, grade and stage of the newlinecolorectal carcinoma cases. newline4. To perform the immunohistochemical markers of newlinemicrosatellite instability (MLH1, MSH2, MSH6, PMS2) in the newlinerepresentative tissue sections of colorectal carcinoma cases. newline5. To study the expression of markers of microsatellite newlineinstability (MLH1, MSH2, MSH6, PMS2) in the newlinerepresentative sections of tissues. newline6. To correlate the microsatellite stability/instability status with newlinedemographic features and tumour characteristics such as site, newlinemorphology, grade, pathological stage, presence of tumour newlinedeposits, lymphovascular and/or perineural invasion |
Pagination: | |
URI: | http://hdl.handle.net/10603/530066 |
Appears in Departments: | Department of Pathology |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01_title.pdf | Attached File | 80.3 kB | Adobe PDF | View/Open |
02_prelim pages.pdf | 363.34 kB | Adobe PDF | View/Open | |
03_content.pdf | 114.17 kB | Adobe PDF | View/Open | |
04_abstract.pdf | 74.76 kB | Adobe PDF | View/Open | |
05_chapter 1.pdf | 162.27 kB | Adobe PDF | View/Open | |
06_chapter 2.pdf | 850.46 kB | Adobe PDF | View/Open | |
07_chapter 3.pdf | 184.12 kB | Adobe PDF | View/Open | |
08_chapter 4.pdf | 461.55 kB | Adobe PDF | View/Open | |
09_chapter 5.pdf | 165.85 kB | Adobe PDF | View/Open | |
10_annexures.pdf | 3.67 MB | Adobe PDF | View/Open | |
80_recommendation.pdf | 87.12 kB | Adobe PDF | View/Open |
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