Development of higher coordinated compounds of silicon synthetic aspects structural characterization and their applications

Abstract

The present thesis incorporates the development of higher coordinated compounds of silicon, specifically silatranes and their characterization using different spectroscopic techniques such as FT-IR, 1 H NMR and 13C NMR. The synthesized compounds have been investigated for their solvatochromic, ionochromic and biological properties using spectroscopic as well as computational techniques. Moreover, the theoretical analysis using DFT/TDDFT approach has annotated to get an insight into the coordination mode of ligand to metal ion. Furthermore, the molecular docking studies have been performed for computer-based predictions and investigation of binding interactions between synthesized ligands and proteins. newline