Green synthesis and optimization of zinc oxide quantum dots from bionanocomposite for its therapeutic applications

Abstract

newline In the current scenario, nanoscience and nanotechnology involves in diverse applications such as medicine, textiles, electronic, agriculture and mechanical industries. Green technology for nanoparticles synthesis is considered to be of great significance in biomedical applications. Quantum Dots (QDs) are colloidal semiconductor nanocrystals having ~1-10 nm diameters. Low-dimensional semiconductor QDs have received great attention in the field of biomedical applications like diagnosis and therapy. The QDs can be made based on different materials such as inorganic semiconducting materials, carbon, and graphene obtained from natural sources. QDs shows size-dependent optical and electronic properties and these properties makes QDs as a good material in the field of biomedical applications such as bio imaging and sensing, drug delivery, diagnostics, cancer therapy etc. Green chemistry is a set of concepts in the fabrication, structure, and biological processes that reduce or eliminate synthetical use or processing of toxic materials. Plant based methods are thus an appealing platform for the preparation of metal oxide NPs and QDs due to their cost effective approach, consistency, short production time, and performance. Quercetin, ß-sitosterol, alkaloids, tannins, terpenoids, carotenoids, and polyphenolic flavonoids are among the phytochemicals found in the Azadirachta indica, Aloe vera, C. roseus, Curcumin and Neem essential oil. These phytochemicals have the potential to be used in the synthesis of ZnO-based nanostructures as reducing and capping agents. This thesis focusses on the preparation of QDs from Bionanocomposites that are biocompatible.