Investigation of Anti obesity Potential of Heartwood Hydroalcoholic Extract of Acacia suma Roxb in High Fat Diet Fed C57BL 6 Mice

Abstract

Background: Obesity is defined as Chronic complex diseases characterize with excessive newlineadiposity that impairs health. BMI is a major indicator of obesity measured as weight in newlinekilogram divided by height in meter-square. Other than obesity metabolic syndrome includes newlineglucose intolerance, insulin resistance, lipid disturbance, hypertension and cardiac diseases. newlineAim and objectives: The study aimed to investigate the anti-obesity effect of Acacia suma newline(Roxb.) in the experimental animal model. The objectives of this study are to predict the newlinebinding affinity of phytoconstituents from Acacia suma using in-silico approach and newlineinvestigation of anti-obesity activity of heartwood hydroalcoholic extract of Acacia suma newlineusing 3T3-L1 cell line and in experimental animal model. newline