Biosynthesis and Applications of Cyclic beta 13 16 Glucans Extracted from Bradyrhizobium Japonicum Bacteria

Abstract

Every aspect of the creation has something very unique to itself which would be known only if pursued tirelessly. One of many such aspects is the world of microbes and their metabolites. For all said and done, many aspirants of Science have worked, are working and would also be working towards knowing the still large unknown. In that pursuit of knowing the unknown based on what is known, an attempt has been made in the form of this work entitled Biosynthesis and Applications of Cyclic and#946;-(1and#8594;3),(1and#8594;) glucans extracted from Bradyrhizobium japonicum . newlineThe Cyclic and#946;-glucans are cell concomitant polysaccharides that are found almost solely in bacteria of the Rhizobiaceae family as cell surface carbohydrates. They are major cell envelope constituents. These molecules have been understood to function both for the independent active states of these bacteria and during the course of plant infection. The cyclic and#946;-glucans of current interest are produced in Bradyrhizobium and the glucose residues are linked by both and#946;-(1and#8594;3) and and#946;-(1and#8594;6) glycosidic bonds. The cell associated polysaccharides from Bradyrhizobium species, cyclic and#946;-(1and#8594;3),(1and#8594;6)-glucans (CBG) are unique due to their smaller ring size compared to those from other Rhizobiaceae family. While these molecules contain glucose as the only hexose monomer, at times they may be highly substituted with non-sugar moieties such as sn-1-phosphocholine. The degree of polymerization (DP) of these cyclic and#946;-glucans ranges from 10 to 13 units. Cyclic structure of these glucans results in a cavity and hence can be a prospective inclusion agent in the food and pharmaceutical industries, as well as in the separation sciences. newline