Shodhganga : a reservoir of Indian theses @ INFLIBNET
The Shodhganga@INFLIBNET Centre provides a platform for research students to deposit their Ph.D. theses and make it available to the entire scholarly community in open access.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/5003
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.coverage.spatial | -- | en_US |
| dc.date.accessioned | 2012-10-26T10:18:46Z | - |
| dc.date.available | 2012-10-26T10:18:46Z | - |
| dc.date.issued | 2012-10-26 | - |
| dc.identifier.uri | http://hdl.handle.net/10603/5003 | - |
| dc.description.abstract | The present thesis focuses on the evaluation of human embryonic stem cells (hESC) as a model to understand the propensity of independently derived cell lines towards specific germ layers if any. Obtaining a purer population of desired cell type in large numbers based on this inherent potential of hESC was the next aim. Finally, this study explores the feasibility of these hESC and their derivatives in determination of toxic effects of known drugs and drug solvents so as to make available a humanized cell-based platform for drug screening and toxicity testing. | en_US |
| dc.format.extent | -- | en_US |
| dc.language | English | en_US |
| dc.relation | No. of references 217 | en_US |
| dc.rights | university | en_US |
| dc.title | Evaluation of the potential of embryonic stem cells esc and their derivatives as a model for drug screening and toxicity | en_US |
| dc.title.alternative | en_US | |
| dc.creator.researcher | Pal, Rajarshi | en_US |
| dc.subject.keyword | Embryonic Stem Cells | en_US |
| dc.subject.keyword | Embryoid Bodies | en_US |
| dc.subject.keyword | Hepatocyte Differentiation | en_US |
| dc.subject.keyword | Cytotoxicity | en_US |
| dc.subject.keyword | Drug Screening | en_US |
| dc.description.note | Summary and Bibliography included | en_US |
| dc.contributor.guide | Bhonde, Ramesh R | en_US |
| dc.publisher.place | Manipal | en_US |
| dc.publisher.university | Manipal University | en_US |
| dc.publisher.institution | Manipal Institute of Regenerative Medicine | en_US |
| dc.date.registered | 14/11/08 | en_US |
| dc.date.completed | 05/12/11 | en_US |
| dc.date.awarded | 2012 | en_US |
| dc.format.dimensions | -- | en_US |
| dc.format.accompanyingmaterial | None | en_US |
| dc.type.degree | Ph.D. | en_US |
| dc.source.inflibnet | INFLIBNET | en_US |
| Appears in Departments: | Manipal Institute of Regenerative Medicine | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01_title.pdf | Attached File | 89.89 kB | Adobe PDF | View/Open |
| 02_certificate.pdf | 137.54 kB | Adobe PDF | View/Open | |
| 03_abstract.pdf | 80.44 kB | Adobe PDF | View/Open | |
| 04_declaration.pdf | 170.79 kB | Adobe PDF | View/Open | |
| 05_acknowledgement.pdf | 88.51 kB | Adobe PDF | View/Open | |
| 06_contents.pdf | 161.76 kB | Adobe PDF | View/Open | |
| 07-list of tables.pdf | 4.5 kB | Adobe PDF | View/Open | |
| 08_list of figures.pdf | 9.83 kB | Adobe PDF | View/Open | |
| 09_abbreviations.pdf | 150.53 kB | Adobe PDF | View/Open | |
| 10_objectives.pdf | 80.72 kB | Adobe PDF | View/Open | |
| 11_chapter 1.pdf | 365.44 kB | Adobe PDF | View/Open | |
| 12_chapter 2.pdf | 322.62 kB | Adobe PDF | View/Open | |
| 13_chapter 3.pdf | 1.09 MB | Adobe PDF | View/Open | |
| 14_chapter 4.pdf | 1 MB | Adobe PDF | View/Open | |
| 15_chapter 5.pdf | 721.01 kB | Adobe PDF | View/Open | |
| 16_chapter 6.pdf | 1.2 MB | Adobe PDF | View/Open | |
| 17_conclusion.pdf | 80.48 kB | Adobe PDF | View/Open | |
| 18_summary.pdf | 173.67 kB | Adobe PDF | View/Open | |
| 19_bibliography.pdf | 370.95 kB | Adobe PDF | View/Open |
Items in Shodhganga are licensed under Creative Commons Licence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).
Altmetric Badge: