Identifying Antimicrobial Potential of Phytomolecules Isolated from Moringa Oleifera Lam_Moringaceae

Abstract

The antibacterial potential of different extracts of Moringa oleifera was screened against four bacteria using disc diffusion assay. Lowest concentration of the extract, which inhibits any visual microbial growth after treatment with p-iodonitrotetrazolium violet, was considered to be minimum inhibitory concentration (MIC). Methanol extract of Moringa oleifera exhibited good activity against all the bacteria tested and the MIC was recorded in range of 9.375-37.5 and#956;g/ml.The other extracts of Moringa oleifera showed antimicrobial activity in a range of 75-1200 and#956;g/ml. newlineThe antifungal activity of different extracts of Moringa oleifera were tested against plant pathogenic fungi Rhizopus stolonifera and Micros Porum gypsum by disc diffusion method. The plant leaves were extracted with various solvents like methanol, aqueous. Among the different extracts tested, the methanolic extracts showed maximum antifungal activity against. newlineThe emergence and spread of antibiotic resistance, as well as the evolution of new strains of disease-causing agents, are of great concern to the global health community. Effective treatment of a disease entails the development of new pharmaceuticals or some potential source of novel drugs. Commonly used medicinal plants of our community could be an excellent source of drugs to fight off this problem. This study is focused on exploring the antimicrobial properties of the plants that are commonly being used as traditional medicines. The antimicrobial potential of four different plant extracts was screened against pathogenic microorganisms. Methanolic extracts of Moringa oleifera were subjected to a test of their antimicrobial properties by disc diffusion method. The result indicated that most of the extracts exhibited antimicrobial properties. The experiment confirmed the efficacy of some selected plant extracts as natural antimicrobials and suggested the possibility of employing them in drugs for the treatment of infectious diseases caused by the test organisms. newline newline