Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/488940
Title: | Applicability of tamarind and Neem gums as Polymers in the design of extended Release Matrix tablets |
Researcher: | RAVI KUMAR NAMBALLA |
Guide(s): | K. V. RAMANA MURTHY and J. VIJAYA RATNA |
Keywords: | Clinical Pre Clinical and Health Pharmacology and Pharmacy Pharmacology and Toxicology |
University: | Andhra University |
Completed Date: | 2022 |
Abstract: | quotABSTRACT newlineIn the current research work, it was aimed to develop extended newlinerelease matrix tablets using neem (Azadiractha indica) and tamarind newline(Tamarindus indica) gums as polymers and aceclofenac (200 mg per newlinematrix tablet) and vildagliptin (100 mg per matrix tablet) as model drugs. newlineFrom the screening experiments using both gums and drugs in newlinecomparison with known synthetic polymer HPMC K100M, gum levels for newlineeach drug formulation were finalized for extension of drug release up to newline24 hours from the matrix tablets prepared using wet granulation newlinetechnique. All the powder blends and matrix tablets were evaluated for newlineflow and tablet properties. In vitro dissolution studies were carried out newlineusing pH 6.8 phosphate buffer for both drugs using USP apparatusquot newline newline |
Pagination: | 334 pg |
URI: | http://hdl.handle.net/10603/488940 |
Appears in Departments: | Department of Pharmacy |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01_title.pdf | Attached File | 5.44 MB | Adobe PDF | View/Open |
02_prelim pages.pdf | 5.47 MB | Adobe PDF | View/Open | |
03_content.pdf | 5.44 MB | Adobe PDF | View/Open | |
04_abstract.pdf | 5.44 MB | Adobe PDF | View/Open | |
05_chapter 1.pdf | 5.48 MB | Adobe PDF | View/Open | |
06_chapter 2.pdf | 5.46 MB | Adobe PDF | View/Open | |
07_chapter 3.pdf | 5.47 MB | Adobe PDF | View/Open | |
08_chapter 4.pdf | 5.49 MB | Adobe PDF | View/Open | |
09_chapter 5.pdf | 5.51 MB | Adobe PDF | View/Open | |
10_chapter 6.pdf | 5.47 MB | Adobe PDF | View/Open | |
11_chapter 7.pdf | 5.5 MB | Adobe PDF | View/Open | |
12_annexures.pdf | 5.46 MB | Adobe PDF | View/Open | |
80_recommendation.pdf | 5.51 MB | Adobe PDF | View/Open |
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