Exploring the structure and dynamics fo proteins in non native states using fluorescence spectroscopy

Abstract

In the present thesis structure and dynamics of non native states in proteins are discussed under different experimental conditions Owing to their conformation heterogeneity their involvement in protein folding pathway including their role in different protein misfolding diseases non native forms of protein are important both for basic and applied areas of biological science Local structures in protein under extreme denaturing conditions are known as residual structures and are believed to a