Biophysical investigations of hen iysozyme aggregation and its inhibition at alkaline ph

Abstract

Protein aggregation has been considered as undesired product while incorrect folding of proteins It is associated with the many of consequences like neurodegenerative diseases e g AlzheimerDs and ParkinsonDs and non neurodegenerative disease e g Type II diabetes systemic amylodosis recovery of over expressed therapeutics proteins and formulation for the protein drug Protein aggregation occurs through different and complex pathway forming intermediate products like oligomers These o