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http://hdl.handle.net/10603/482973
Title: | Wound healing activity of Tridax procumbens leaf and stem mediated selenium nanoparticles and its chitosan based nanocomposites |
Researcher: | Jaya Priya J |
Guide(s): | Rajesh Kumar S |
Keywords: | Engineering Engineering and Technology Engineering Biomedical |
University: | Saveetha University |
Completed Date: | 2023 |
Abstract: | Since wound care and healing have always been crucial for survival, it connected our focus newlineon the study of healing in general. Wounds are categorised into two groups: open and newlineclosed wounds. In this article we detailed Open wounds: bleeding is obviously present and newlineblood escapes from the body, abrasions, lacerations, punctures, avulsions. Nanoparticles newlineare smallest 10 -9 SI unit, molecule ranged around 1- 100 µm. Also have special qualities newlinelike their shape, size, and physical and chemical properties. NPs are one among the best newlinewound restoration agents due to their wide spectrum of antibacterial properties and quick newlineefficiency with minimum dose. Due to their inability to permeate the cell barrier, newlineconventional wound healing medications have limited promise. The disintegration of the newlinecell membrane, changes to the genes, and inhibition of the manufacture of enzymes are all newlinecomponents of nanoparticles. Green synthesis of selenium nanoparticles and chitosan newlinebased nanocomposites using Tridax procumbens (TP) is a new combination work. In this newlinestudy, Tridax procumbens is a widespread herbaceous weed that was used for SeNPs and newlineSeNCs production. Then it was investigated using in vitro and in vivo studies. The newlinepreliminary characterisations proved the presence of selenium nanoparticles. The UV- Vis newlinespec analysis confirmed the reducing agents present in TP stem, leaf mediated SeNPs and newlineSeNCs by the peak value obtained. FT-IR analysis revealed the presence of some newlinefunctional constituents in the extract. TEM and SEM analysis confirmed the size, shape newlineand structure of TP stem, leaf mediated SeNPs and SeNCs. The anti-bacterial plate assay newlineshowed effective activity against three wound pathogens such as E.coli, S. aureus and P. newlineaeruginosa. The anti-oxidant analysis such as DPPH, FRAP, H2O2 revealed the effective newlinefree radical scavenging activity. The anti-inflammatory analysis such as BSA, EA revealed newlinethe effective inhibitory properties in TP stem, leaf mediated SeNPs and SeNCs. |
Pagination: | |
URI: | http://hdl.handle.net/10603/482973 |
Appears in Departments: | Bio technology |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01_title.pdf | Attached File | 290.55 kB | Adobe PDF | View/Open |
02_prelim pages.pdf | 899.16 kB | Adobe PDF | View/Open | |
03_contents.pdf | 261 kB | Adobe PDF | View/Open | |
04_abstract.pdf | 163.17 kB | Adobe PDF | View/Open | |
05_chapter1.pdf | 530.16 kB | Adobe PDF | View/Open | |
06_chapter2.pdf | 307.12 kB | Adobe PDF | View/Open | |
07_chapter3.pdf | 646.08 kB | Adobe PDF | View/Open | |
08_chapter4.pdf | 316.67 kB | Adobe PDF | View/Open | |
09_chapter5.pdf | 2.91 MB | Adobe PDF | View/Open | |
10_annexures.pdf | 7.51 MB | Adobe PDF | View/Open | |
11_chapter6.pdf | 990.76 kB | Adobe PDF | View/Open | |
80_recommendation.pdf | 306.54 kB | Adobe PDF | View/Open |
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