1. Shodhganga@INFLIBNET
  2. Indian Institute of Technology Guwahati
  3. DEPARTMENT OF BIOSCIENCES AND BIOENGINEERING
Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/481120
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dc.date.accessioned2023-05-03T11:24:32Z-
dc.date.available2023-05-03T11:24:32Z-
dc.identifier.urihttp://hdl.handle.net/10603/481120-
dc.description.abstractIn the present thesis, specific DNA aptamers were screened against breast cancer protein biomarkers Her2 and ER alpha. The aptamers were screened by in-vitro SELEX process from a pool of 1014 number of oligonucleotides. The sensitivity of the candidates were evaluated by isothermal calorimetry and other in-vitro binding studies. To assess the biocompatibility of the selected aptamers, MTT assay was performed in marker positive and negative cancer cell lines and normal cell lines also. Specificit
dc.format.extent
dc.languageEnglish
dc.relation
dc.rightsself
dc.titleAptamers for breast cancer protein markers
dc.title.alternative
dc.creator.researcherSett, Arghya
dc.subject.keywordBiotechnology and Applied Microbiology
dc.subject.keywordLife Sciences
dc.subject.keywordMicrobiology
dc.description.note
dc.contributor.guideBora, Utpal
dc.publisher.placeGuwahati
dc.publisher.universityIndian Institute of Technology Guwahati
dc.publisher.institutionDEPARTMENT OF BIOSCIENCES AND BIOENGINEERING
dc.date.registered2010
dc.date.completed2016
dc.date.awarded2016
dc.format.dimensions
dc.format.accompanyingmaterialNone
dc.source.universityUniversity
dc.type.degreePh.D.
Appears in Departments:DEPARTMENT OF BIOSCIENCES AND BIOENGINEERING

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