Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/480934
Title: | Recombinant sfrps in wnt 946 catenin signaling targeted cancer therapy |
Researcher: | Ghoshal, Archita |
Guide(s): | Ghosh, Siddhartha Sankar |
Keywords: | Biotechnology and Applied Microbiology Life Sciences Microbiology |
University: | Indian Institute of Technology Guwahati |
Completed Date: | 2016 |
Abstract: | Cancer cells are known to lack regulation of cell proliferation due to the aberrant behavior of a myriad of signaling pathways One such pathway is the Wnt signal cascade which is one of the multiple facets responsible for the upregulation of several pro proliferative genes in cancer In non cancerous cells this Wnt pathway is blocked by a family of secretory glycoproteins playing a role in cell growth arrest called the secreted frizzled related proteins sFRPs However these sFRPs are typi |
Pagination: | Not Available |
URI: | http://hdl.handle.net/10603/480934 |
Appears in Departments: | DEPARTMENT OF BIOSCIENCES AND BIOENGINEERING |
Files in This Item:
File | Description | Size | Format | |
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01_fulltext.pdf | Attached File | 2.8 MB | Adobe PDF | View/Open |
04_abstract.pdf | 177.26 kB | Adobe PDF | View/Open | |
80_recommendation.pdf | 243.13 kB | Adobe PDF | View/Open |
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