Shodhganga : a reservoir of Indian theses @ INFLIBNET
The Shodhganga@INFLIBNET Centre provides a platform for research students to deposit their Ph.D. theses and make it available to the entire scholarly community in open access.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/479701
| Title: | Effect of confinement on protein conformation in presence of osmolytes urea and trimethylamine n oxide |
| Researcher: | Borgohain, Gargi |
| Guide(s): | Paul, Sandip |
| Keywords: | Chemistry Chemistry Applied Physical Sciences |
| University: | Indian Institute of Technology Guwahati |
| Completed Date: | 2016 |
| Abstract: | The mechanism by which TMAO provides counteraction against the action of urea and stabilizes protein has been investigated We focus on the effects of urea and TMAO on the folding unfolding equilibrium of protein and put an effort to uncover the molecular basis of denaturation and counteraction mechanisms In Chapter 1 we present a detailed literature review of the mechanism of action of the osmolytes their effects on the protein The reason of choosing REMD Replica Exchange Molecular Dynamic |
| Pagination: | Not Available |
| URI: | http://hdl.handle.net/10603/479701 |
| Appears in Departments: | DEPARTMENT OF CHEMISTRY |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01_fulltext.pdf | Attached File | 3.4 MB | Adobe PDF | View/Open |
| 04_abstract.pdf | 94.5 kB | Adobe PDF | View/Open | |
| 80_recommendation.pdf | 877.75 kB | Adobe PDF | View/Open |
Items in Shodhganga are licensed under Creative Commons Licence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).
Altmetric Badge: