Dynamics and analysis of models for chronic hepatitis b virus infection

Abstract

This thesis investigates several models for hepatitis B virus HBV infection including the incorporation of the dynamics of intracellular HBV DNA containing capsids Firstly we analyze a model for infected hepatocytes capsids and virions along with the homeostatic mechanism of the liver and incorporating a discrete time delay in the production of mature capsids We then present and analyze a modified model where the dynamics of both uninfected hepatocytes and capsids along with infected hepa