Shodhganga : a reservoir of Indian theses @ INFLIBNET
The Shodhganga@INFLIBNET Centre provides a platform for research students to deposit their Ph.D. theses and make it available to the entire scholarly community in open access.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/479302
| Title: | Understanding pyrimidine and aspartate metabolism in the growth and infectivity of leishmania donovani |
| Researcher: | Tiwari, Kartikeya |
| Guide(s): | Dubey, Vikash Kumar |
| Keywords: | Biotechnology and Applied Microbiology Life Sciences Microbiology |
| University: | Indian Institute of Technology Guwahati |
| Completed Date: | 2017 |
| Abstract: | Dihydroorotase the third enzyme of the de novo pyrimidine biosynthesis pathway of Leishmania donovani was cloned expressed and biochemically characterized in both directions of enzymatic reactions The data revealed a preference for biologically significant forward direction The forward direction enzymatic reaction shows acidic pH optimum in contrast to slightly alkaline pH optimum of reverse reaction Further the enzyme shows both tetrameric and dimeric structures in equilibrium Biotin su |
| Pagination: | Not Available |
| URI: | http://hdl.handle.net/10603/479302 |
| Appears in Departments: | DEPARTMENT OF BIOSCIENCES AND BIOENGINEERING |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01_fulltext.pdf | Attached File | 9.4 MB | Adobe PDF | View/Open |
| 04_abstract.pdf | 132.12 kB | Adobe PDF | View/Open | |
| 80_recommendation.pdf | 779.34 kB | Adobe PDF | View/Open |
Items in Shodhganga are licensed under Creative Commons Licence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).
Altmetric Badge: