Effect of nigella sativa on lipid profile of hyperlipidemic adult indian population

Abstract

Hyperlipidemia is generally inherent and it increases the probability of diseases of the blood vessels that can lead heart problems and stroke. This being main cause of cardio vascular diseases in most of the cases. There are multiple causes of this disorder which are eating habits, lifestyle, hereditary etc. and having a prevalence of 38.7 % . The aim of conducting this study was to assess the effect of Nigella Sativa Spice Seed Powder Capsules on the lipid profile of hyperlipidemic Indian adults. It has also been found that Nigella Sativa has many other medicinal properties which would be beneficial to the patients other than just lowering their high lipid levels. The study was conducted under the department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Manav Rachna International Institute of Research and Studies. Different medical centers and in house clinics from all the four zones of Faridabad were taken and a sample size of 100 adults with hyperlipidemia were selected. These adults were divided into two groups namely Experimental and Non-experimental. Both the groups were given diet counseling for hyperlipidemia with a run in period of 1 month along with Physical activity of moderate level. The study was double blind randomized trial. While Experimental group was given capsules of Nigella sativa seed powder with an intake of 2 gm per day, the non experimental group were given placebo which was capsules of wheat germ powder of 2 gms per day. The lipid profiles were checked after a period of 3 months. The data was analyzed on SPSS version 21. The study revealed that post intervention the mean cholesterol of experimental group was 193.20+15.77 mg/dl, while that of non experimental group was 211.42+11.23 mg/dl and the difference was statistically significant. There was more reduction in the total cholesterol of the group that was given Nigella Sativa capsules than the group which was given placebo capsules. (Plt0.05) The mean HDL of the experimental group was 43.13+4.62 mg/dl, while that of the