Copper catalyzed cascade c h functionalization and c n bond formation synthesis of functionalised benzimidazoles

Abstract

The thesis contains five chapters which contains synthesis of benzimidazole derivatives which are important structural scaffolds due to their interesting biological and medicinal properties The chapter one covers the recent developments in the construction of benzimdiazoles Considerable progress has thus been made using cross coupling and C H functionalization strategies The chapter two describes the Cu catalyzed oxidative three components coupling of anilines aldehydes and TMSN3 in the pres