Studies on Prevention of Rheumatoid Arthritis by Using Selected Plants

Abstract

A chronic inflammatory condition called arthritis causes joint degeneration via the action of metalloproteases, cytokines, and chemokines. There is a startling absence of historical evidence for rheumatoid arthritis, leading experts to hypothesise that it is a relatively recent illness. (Hansen, 1995). The periarticular synovial tissues and synovial joints are also impacted by the systemic illness. Any joint may be affected, but often it begins with the little bones in the hands and feet. Most of the joints are damaged in serious conditions. As the illness worsens, several other organs get affected due to its systemic nature. Extra-articular involvement may have signs and consequences include fever, weight loss, weakness or weariness, enlarged lymph nodes, anaemia, nodules, dry eyes, fibrosis of the lungs, fluid in the chest cavity, vasculitis, neuropathy, and renal disease. newlineThe synovial membrane thickens and inflames as a result of an auto-immune process, and inflammatory cells penetrate the membrane, which is the primary joint pathology in rheumatoid arthritis. As a consequence, the cartilage and joint gradually deteriorate over time, increasing swelling and discomfort. Initial manifestations of the illness vary. If left untreated, the disorder may become aggressive and destructive, progressing quickly and leaving a person with significant physical handicap. Symptoms can sometimes appear as a single episode of stiff and painful joints that may last many months. (Young, 2000). Numerous factors driving this disease, including changing Indian lifestyle trends, obesity, high levels of stress, ageing, inadequate sleep, sedentary lifestyle, decreased physical activity, and poor eating habits, contribute to the rapid rise of rheumatoid arthritis in India and related metabolic disorders. Along with a greatly higher chance of early mortality, the condition increases the risk of many other illnesses such as intestinal pathologies, cardiovascular disease, pulmonary dysfunction, and renal abnormalities. (Jonsson, 2008). Rh