Perturbation of amyloidogenic conditions of hen lysozyme inhibition thereof by naturally occurring osmolytes and numeric code of amino acids

Abstract

This thesis starts by recognizing seminal discovery of lysozyme amyloid made by point mutations in human Lysozyme Subsequently several in vitro conditions were developed to make lysozyme both Hen and Human amyloid but one condition acidic pH elevated temperatures has swamped all others viz alkaline pH at 25oC concentrated solution of ethanol at 25oC moderate concentration of Guandinium Hydrochloride at elevated temperature All conditions deserve attention if we have to reach to the cor