Shodhganga : a reservoir of Indian theses @ INFLIBNET
The Shodhganga@INFLIBNET Centre provides a platform for research students to deposit their Ph.D. theses and make it available to the entire scholarly community in open access.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/465313
| Title: | Activity studies of indoleamine 2 3 dioxygenase 1 enzyme |
| Researcher: | Roy, Ashalata |
| Guide(s): | Manna, Debasis |
| Keywords: | Chemistry Chemistry Applied Physical Sciences |
| University: | Indian Institute of Technology Guwahati |
| Completed Date: | 2018 |
| Abstract: | Immunosuppressive enzyme indoleamine 2 3 dioxygenase 1 IDO1 plays a pivotal role in regulating the metabolism of L tryptophan L Trp through kynurenine pathway which is a well established therapeutic target for the treatment of diseases associated with immunosuppression Under pathophysiological conditions the expression of IDO1 enzyme from its mRNA gets highly up regulated in response to inflammatory signals like interferon 206 179 within the immune system Up regulation of the IDO1 enzyme is |
| Pagination: | Not Available |
| URI: | http://hdl.handle.net/10603/465313 |
| Appears in Departments: | DEPARTMENT OF CHEMISTRY |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01_fulltext.pdf | Attached File | 7.75 MB | Adobe PDF | View/Open |
| 04_abstract.pdf | 379.43 kB | Adobe PDF | View/Open | |
| 80_recommendation.pdf | 209.1 kB | Adobe PDF | View/Open |
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