Strategies for the diastereoselective synthesis of glycosides by conformational bias

Abstract

The thesis entitled 8220 Strategies for the Diastereoselective Synthesis of Glycosides byConformational Bias 8221 is divided into five chapters Chapter one demonstrates brief ideasabout the importance of glycoconjugates and oligosaccharide and stereo selective synthesisof glycoconjugates Chapter two describes hypervalent iodine mediated stereo and regioselectivesynthesis of C 2 deoxy glycosides and amino acid glycoconjugates In chapter three we have determined the influence of steric crowding on the diastereoselectivearabinofuranosylation In chapter four we have exploited Reciprocal Donor Acceptor Selectivity RDAS to assemble hencontapentasaccharide 51units of mycobacterialLipoarabinomannan In chapter five Reciprocal Donor Acceptor Selectivity RDAS for thesynthesis of four possible hybrid isomers of Araf Ribf glycolipids at disaccharide andpentasaccharide level was described newline newline