A Study Of Correlation Between Cord Blood Lipid Profile And Anthropometry In Infants Of Diabetic Mothers

Abstract

Gestational Diabetes Mellitus (GDM) newlineAny degree of glucose intolerance with onset or first newlinerecognition during pregnancy is termed as gestational diabetes (1). newlineThe incidence of GDM is around 7% of all pregnancies and the newlineprevalence ranges from 1% to 14%. The prevalence is expected to newlineincrease as the epidemic of obesity continues (2). GDM is newlinecharacterized by pancreatic and#946;-cell function that is insufficient to newlinemeet the body s insulin needs. GDM imposes a risk for both mother newlineand child as the risk of cesarean and operative vaginal delivery, newlinemacrosomia, shoulder dystocia, neonatal hypoglycemia and newlinehyperbilirubinemia is increased (3). Women with a history of GDM newlineare also at an increased risk of developing type 2 diabetes mellitus newline(T2DM) in later years and their children have a higher risk of newlinedeveloping obesity and T2DM early in life (4). The clinical newlinedetection of GDM is brought about in different ways in different newlinecountries. GDM is detected by 1) clinical risk assessment 2) glucose newlinetolerance screening and 3) formal glucose tolerance testing. newlineSo, it is essential to increase the awareness of maintaining newlinestrict diabetic control during the antenatal period which in turn will newlinehelp in reduction in development of CVD in later life of fetus. The newlineassociation between cord blood lipids/lipoproteins, with their newlineimplication on anthropometric measures at birth, and further newlinedevelopment of adult cardiac diseases are not fully understood. newlineTherefore, this study is aimed to assess cord blood lipid profile of newlineneonates at birth and their relation to different anthropometric newlinemeasures newline