Exploring the Self-Aggregation of Short Peptides in Aqueous Environment for Various Applications

Abstract

The thesis “Exploring the Self-Aggregation of Short Peptides in Aqueous Environment for Various Applications” deals with the design and applications of new short aggregating peptide with the different non-covalent interactions. Chapter 1 is a brief introduction of peptide based aggregations with up to date literature review. Chapter 2 defines the combination of cation-π and charge-transfer interactions within a donor-acceptor pair to form self-healing hydrogel. Chapter 3 delineates the light-induced syneresis by a water insoluble peptide-hydrogel and effective removal of small molecule waste contaminants. Chapter 4 deals with charge transfer complexation aided control over the reaction pathway. Chapter 5 illustrates protection and glutathione responsive delivery of proteins by an ultrashort peptide hydrogel.