Status of hyperlipidemia in random donor platelets in repeat and one time blood donors

Abstract

newline Donor selection has a vital role in transfusion medicine. So there is a need to devise a protocol that could prevent the loss of blood donors and donations to be safe for the donors and recipients. Thus, all the risk factors associatied with blood transfusions need to be investigated thoroughly, nonetheless, wise screening and careful selection of donor could be a small but effective step to start with. Thus, in order to maintain a healthy donor pool with limited side effects to the blood recipients, it is important to look at several factors during the selection of regular voluntary blood donors. Blood donation has been linked to improved health outcomes in studies. When compared to one/single time donors, repeat donors have a 33-88 percent lower risk of cardiovascular disease. Therefore, this study aimed to assess a correlation between donor s history with lipid and haematological parameters and to correlate the haematological parameters and lipid parameters in blood donors. newlineThis prospective study comprised of 326 voluntary blood donors. Donors who met the inclusion criteria were enrolled in the study. All the included blood donors were grouped into one/single time (n=205) and repeat donors (n=121). The donors willing to participate in the study were called for fasting blood sample collection at the Department of Transfusion Medicine, King George s Medical University, from December 2016 to March 2018. Age, sex as well anthropometric measurement such as height, weight and BMI were recorded. Information regarding smoking status, intake of lipid rich diet, alcohol and OCPs intake, family history of heart diseases and type of physical activity (sedentary or physical active) were recorded in a custom designed questionnaire. The entire participant was personally interviewed to obtain written consent. 9-12 hours fasted donors samples were taken next day after blood donation. Finger prick test was done for haematological analysis (platelet parameters and NLR,PLR) by fully automated haematology analyser