Reactivity Studies of 4-Hydroxydithiocoumarin: Design & Synthesis of Novel Bioactive Molecules

Abstract

"The thesis entitled “Reactivity Studies of 4-Hydroxydithiocoumarin: Design & Synthesis of Novel Bioactive Molecules” has been compiled into six chapters based on the experimental results and findings carried out by me during the entire research period. Chapter 1 provides a brief overview of organosulfur compounds and their importance. In addition, the reason for choosing 4-hydroxydithiocoumarin as the key starting material for the synthesis of novel bioactive molecules. Chapter 2 elaborates on the synthesis of 3-sulfenyl derivatives. Chapter 3 describes the synthesis of α-thiocarbonyl compounds. Chapter 4 illustrates the synthesis of vinyl sulfides and thioethers. Chapter 5 demonstrates the synthesis of 1,4-oxathiin derivatives. Chapter 6 elucidates the synthesis of β-hydroxysulfides and β-aminosulfides by ring-opening reactions."