Structural control of peptide nucleic acid rotamers aza pna and optical properties of gemdimethyl pna bimodal pna monomers and oligomers

Abstract

The thesis entitled 8220 Structural control of Peptide Nucleic Acid PNA rotamers and their fluorescence properties aza PNA gemdimethyl G PNA and C 945 S bm PNA monomers and oligomers 8221 describes studies done on the synthesis characterisation and rotamer study of novel aza PNA monomers 945 946 gemdimethyl guanine PNA C 945 S acetamido bm PNA monomers and oligomers The effect of intramolecular H bonding in C 945 NH aza PNA and gem dimethyl substitution induced conformational constraint on rotamer selectivity and the fluorescence properties are explored in this work The thesis is presented in five chapters newline newline