Shodhganga : a reservoir of Indian theses @ INFLIBNET
The Shodhganga@INFLIBNET Centre provides a platform for research students to deposit their Ph.D. theses and make it available to the entire scholarly community in open access.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/429604
| Title: | Formulation and evaluation of gastroretentive Dosage form of calcium |
| Researcher: | Manasa Moganti |
| Guide(s): | H.N.Shivakumar |
| Keywords: | Calcium carbonate; gastro retention; bioavailability; floating lag time; raft forming in situ gelling system; tablet Clinical Pre Clinical and Health Pharmacology and Toxicology |
| University: | KLE University |
| Completed Date: | 2021 |
| Abstract: | Background: newlineCalcium is mainly absorbed from the stomach and upper gastro intestinal tract and newlinedue to site specificity and pH dependency leading to lower bioavailability and it newlinequickly passes from the absorption site. In such scenario, gastro retentive drug newlinedelivery system could be potential alternative to overcome the limitations associated newlinewith currently available dosage forms. newlineObjective: To develop and evaluate gastroretentive systems as sigle unit bilayer newlinetablets and insitu gelling raft forming solution of calcium carbonate (CC) with newlineobjective to prolong the gastric residence time (GRT) and thereby increasing the newlinebioavailability. newline |
| Pagination: | |
| URI: | http://hdl.handle.net/10603/429604 |
| Appears in Departments: | Faculty of Pharmacy |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 80_recommendation.pdf | Attached File | 642.88 kB | Adobe PDF | View/Open |
| manasa moganti.pdf | 9.25 MB | Adobe PDF | View/Open |
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