Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/428844
Title: | Regioselective C H Amidation Reactions using Directing Group Strategy and its Application in Organic Synthesis |
Researcher: | Hande, Akshay |
Guide(s): | Prabhu, K R |
Keywords: | Chemistry Chemistry Organic Physical Sciences |
University: | Indian Institute of Science Bangalore |
Completed Date: | 2019 |
Abstract: | The thesis represents an approach for the C-H bond activation using directing group strategy. The C-H activation happens through five/six-membered metallacycle through concerted metallation deprotonation. Further functionalization leads to C-N formation in the presence of an amidating reagent dioxazolone. Dioxazolone a robust and efficient amidating reagent has been utilized for the C-N bond formation reaction. The strategy has been applied for the azobenzene derivatives for further benzotriazole heterocycle synthesis. The 7-amino indoline derivatives have been synthesized at the ambient condition which endures an application in bioactive molecules. Subsequently, the amidated 2-amido aldehydes and ketones derivatives have been utilized for the synthesis of quindolinone alkaloids |
Pagination: | xiv, 231 p. |
URI: | http://hdl.handle.net/10603/428844 |
Appears in Departments: | Organic Chemistry |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
01_title.pdf | Attached File | 87.26 kB | Adobe PDF | View/Open |
02_prelim pages.pdf | 193.05 kB | Adobe PDF | View/Open | |
03_table of contents.pdf | 75.53 kB | Adobe PDF | View/Open | |
04_abstract.pdf | 593.03 kB | Adobe PDF | View/Open | |
05_chapter 1.pdf | 888.78 kB | Adobe PDF | View/Open | |
06_chapter 2.pdf | 3.78 MB | Adobe PDF | View/Open | |
07_chapter 3.pdf | 4.8 MB | Adobe PDF | View/Open | |
08_chapter 4.pdf | 6.77 MB | Adobe PDF | View/Open | |
09_annexure.pdf | 72.5 kB | Adobe PDF | View/Open | |
80_recommendation.pdf | 6.86 MB | Adobe PDF | View/Open |
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