Development of new synthetic protocols for the synthesis of some bioactive scaffolds under greener conditions

Abstract

The present thesis entitled Development of new synthetic protocols for the synthesis of some bioactive scaffolds under greener conditions comprises of two parts --- Chapter 1 and Chapter 2. The entire thesis is summarized as follows: Chapter 1 is related to literature reviews and contains four sections whereas Chapter 2 is based on original research work. Chapter 1 describes the catalytic activities of four different metal-free organocatalysts. Viz., camphor sulfonic acid (CSA), p-sulfonic acid calix[n]arenes, p-dodecylbenzenesulfonic acid (DBSA), Saccharin (1,2-benzisothiazol-3(2H)-one-1,1-dioxide). Chapter 2 describes synthesis of diverse biologically promising scaffolds by using metal-free organo-catalysts such as mandelic acid, itaconic acid or camphor sulfonic acid under various reaction conditions. newline