1. Shodhganga@INFLIBNET
  2. Indian Institute of Science Bangalore
  3. Molecular Biophysics Unit
Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/426331
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dc.date.accessioned2022-12-17T09:48:10Z-
dc.date.available2022-12-17T09:48:10Z-
dc.identifier.urihttp://hdl.handle.net/10603/426331-
dc.description.abstracthis thesis describes the structure determination of peptides found in marine cone snails venom at atomic resolution and their biological activity. Chapter 1 gives a brief introduction to the cone snails, conopeptides, and basic NMR to determine the tertiary structure. Chapter 2 describes the biological activity of three single disulfide conopeptides from different cone snails. Chapter 3 and 4 describes tertiary structure of novel single disulfide peptide Czon1107 from Conus zonatus and its analogues and Cca1669 from Conus caracteristicus respectively. Chapter 5 investigates the influence of the pro on the mature toxin of three disulfide conotoxin. The structural studies described here have been carried out using high-resolution NMR spectroscopic methods newline-
dc.format.extentxxix, 229-
dc.languageEnglish-
dc.rightsuniversity-
dc.titleSolution structures and conformational isomerism of novel conopeptides from Indian marine cone snails-
dc.creator.researcherMadhan Kumar, M-
dc.subject.keywordBiophysics-
dc.subject.keywordLife Sciences-
dc.subject.keywordMolecular Biology and Genetics-
dc.contributor.guideSarma, Siddhartha P-
dc.publisher.placeBangalore-
dc.publisher.universityIndian Institute of Science Bangalore-
dc.publisher.institutionMolecular Biophysics Unit-
dc.date.completed2020-
dc.date.awarded2021-
dc.format.dimensions30-
dc.format.accompanyingmaterialNone-
dc.source.universityUniversity-
dc.type.degreePh.D.-
Appears in Departments:Molecular Biophysics Unit

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01_title.pdfAttached File193.32 kBAdobe PDFView/Open
02_prelim pages.pdf558.09 kBAdobe PDFView/Open
03_content.pdf175.03 kBAdobe PDFView/Open
04_abstract.pdf160.64 kBAdobe PDFView/Open
05_chapter 1.pdf519.22 kBAdobe PDFView/Open
06_chapter 2.pdf1.09 MBAdobe PDFView/Open
07_chapter 3.pdf10.74 MBAdobe PDFView/Open
08_chapter 4.pdf9.44 MBAdobe PDFView/Open
09_annexure.pdf673.14 kBAdobe PDFView/Open
80_recommendation.pdf5.96 MBAdobe PDFView/Open
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