Please use this identifier to cite or link to this item: http://hdl.handle.net/10603/426173
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dc.date.accessioned2022-12-17T08:21:23Z-
dc.date.available2022-12-17T08:21:23Z-
dc.identifier.urihttp://hdl.handle.net/10603/426173-
dc.description.abstractThe thesis is entitled as quotDevelopment of Novel NMR Methodology and Investigation of Challenging Chemical Problems quot. The research work reported in this thesis is mainly carried out in two directions. The initial focus being the design of new pulse sequence by manipulating the spin dynamics to precisely measure the scalar couplings of the selected proton from the complex NMR spectrum. The developed novel pulse sequence efficiently suppresses the evolution of unwanted couplings and eradicates the uninformative intense axial peaks that are inherent in the selective refocusing experiments, thereby yielding the clean spectrum devoid of any type of artefacts. In the other part, the one and two dimensional NMR spectroscopic has been extensively employed to address challenging and interesting chemical problems, such as, chiral analysis where a new ternary ion-pair protocol has been developed for the spectroscopic configurational assignment of various chiral acids and esters, and the two- and three-centered hydrogen bonding interactions in molecules of pharmacological importance. It has been indubitably established that the strength of intramolecular hydrogen bond is controlling the conformational populations in one set of the investigated molecules and the geometrical constraints in addition to the cooperativity between the individual hydrogen bonds of another set of bifurcated molecules imparts full rigidification to the molecular structure making the system relatively very stable and hindering the breaking of hydrogen bond by even the high polarity solvent DMSO.
dc.format.extentxvii, 236p.
dc.languageEnglish
dc.relation
dc.rightsuniversity
dc.titleDevelopment of Novel NMR Methodology and the Investigation of Challenging Chemical Problems
dc.title.alternative
dc.creator.researcherArya, Neeru
dc.subject.keywordChemistry
dc.subject.keywordChemistry Inorganic and Nuclear
dc.subject.keywordPhysical Sciences
dc.description.note
dc.contributor.guideSuryaprakash, N
dc.publisher.placeBangalore
dc.publisher.universityIndian Institute of Science Bangalore
dc.publisher.institutionSolid State and Structural Chemistry Unit
dc.date.registered
dc.date.completed2020
dc.date.awarded2020
dc.format.dimensions30 cm.
dc.format.accompanyingmaterialNone
dc.source.universityUniversity
dc.type.degreePh.D.
Appears in Departments:Solid State and Structural Chemistry Unit

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01_title.pdfAttached File79.7 kBAdobe PDFView/Open
02_prelim pages.pdf374.43 kBAdobe PDFView/Open
03_table of contents.pdf240.44 kBAdobe PDFView/Open
04_abstract.pdf143.62 kBAdobe PDFView/Open
05_chapter 1.pdf1.8 MBAdobe PDFView/Open
06_chapter 2.pdf990.71 kBAdobe PDFView/Open
07_chapter 3.pdf2.04 MBAdobe PDFView/Open
08_chapter 4.pdf1.81 MBAdobe PDFView/Open
09_chapter 5.pdf1.63 MBAdobe PDFView/Open
10_annexure.pdf4.45 MBAdobe PDFView/Open
80_recommendation.pdf232.8 kBAdobe PDFView/Open


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