Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/425328
Title: | Safety Studies of Hydroxyapatite Nanoparticles and Polymer Coated Hydroxyapatite Nanoparticles on Drosophila Melanogaster |
Researcher: | Pallavi Dan |
Guide(s): | Sahabudeen, S |
Keywords: | Biotechnology and Applied Microbiology Life Sciences Microbiology |
University: | SRM Institute of Science and Technology |
Completed Date: | 2022 |
Abstract: | Hydroxyapatite (HAp), is a member of the apatite family comprising of Ca/P ratios ranging from 1.57 to 1.67. The exceptional biocompatibility and biodegradability properties have been broadly used in biomedical applications and other purposes such as drug delivery, bone tissue engineering etc. HAp NPs have been combined with different polymeric materials to overcome the limitations such as poor loading properties, and higher flexibility. Studies have reported that HAp NPs caused developmental delays in adult flies and zebra fish models. Therefore, augmented use of HAp NPs warrants the study of its toxic effects in in vivo models. newlineChitosan (CS), is a naturally occurring polymer that is obtained by the deacetylation of chitin commonly present in the shells of crustaceans, insect cuticles etc. Its biodegradable, antimicrobial and antioxidant properties have been the primary reason to be used in several fields such as tissue engineering, biology, food, and pharmaceutical industries. Chitosan has been used against acrylamide (ACR) induced toxicity in Drosophila melanogaster. Herein, |
URI: | http://hdl.handle.net/10603/425328 |
Appears in Departments: | Department of Biotechnology |
Files in This Item:
File | Description | Size | Format | |
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01_title.pdf | Attached File | 241.29 kB | Adobe PDF | View/Open |
02_preliminary page.pdf | 395.27 kB | Adobe PDF | View/Open | |
03_content.pdf | 240.32 kB | Adobe PDF | View/Open | |
04_abstract.pdf | 174.09 kB | Adobe PDF | View/Open | |
05_chapter 1.pdf | 390.61 kB | Adobe PDF | View/Open | |
06_chapter 2.pdf | 325.47 kB | Adobe PDF | View/Open | |
07_chapter 3.pdf | 826.78 kB | Adobe PDF | View/Open | |
08_chapter 4.pdf | 968.07 kB | Adobe PDF | View/Open | |
09_chapter 5.pdf | 912.68 kB | Adobe PDF | View/Open | |
10_chapter 6.pdf | 379.39 kB | Adobe PDF | View/Open | |
11_chapter 7.pdf | 161.85 kB | Adobe PDF | View/Open | |
12_annexures.pdf | 521.32 kB | Adobe PDF | View/Open | |
80_recommendation.pdf | 269.78 kB | Adobe PDF | View/Open |
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