Cell signaling and functions mediated by a serine threonine phosphatase regulatory subunit and related proteins in neurospora crassa

Abstract

In this thesis work I investigated cell functions mediated by the calcineurin B CNB 1 subunit in Neurospora crassa I studied how the mutations in the various EF hand domains of CNB 1 result in diverse phenotypes under stress conditions including calcium Ca2 stress thermotolerance and regulation of the circadian clock in N crassa Furthermore I established genetic interaction of cnb 1 with the nca 2 hsp80 crz 1 frequency frq 1 and white collar wc 1 genes in the regulation the...