Peptide based molecular constructs for cellular targeting and small molecule delivery

Abstract

Advancement in synthesis and characterization protocols and demand of new chemical entities NCE have contributed to the development of peptide based therapeutics The introduction of cell penetrating and tumor homing peptides has opened up new avenues for drug delivery applications using peptides In the present thesis we rationally designed sixteen peptides for targeted drug delivery broadly classified into three different peptide series The conceptual advancement of Series 1 to Series 3 p...