Shodhganga : a reservoir of Indian theses @ INFLIBNET
The Shodhganga@INFLIBNET Centre provides a platform for research students to deposit their Ph.D. theses and make it available to the entire scholarly community in open access.
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10603/421100
| Title: | Investigations into expression and regulation of cystatin a and its implication in breast cancer |
| Researcher: | Dixcy, Jaba Sheeba J M |
| Guide(s): | Limaye, Anil Mukund |
| Keywords: | Engineering Engineering and Technology Engineering Biomedical |
| University: | Indian Institute of Technology Guwahati |
| Completed Date: | 2020 |
| Abstract: | The most perilous attribute of malignant tumors is to metastasize which directly impacts survival Cystatin A CSTA is an endogenous inhibitor of cathepsins which play a significant role in the malignant progression of tumors Loss of CSTA expression shifts the balance towards cathepsins resulting in extensive ECM remodeling tumor invasion and metastasis The precise mechanism behind the loss or regulation of CSTA expression in breast tumors is not known In this study we elucidated the me... |
| Pagination: | Not Available |
| URI: | http://hdl.handle.net/10603/421100 |
| Appears in Departments: | DEPARTMENT OF BIOSCIENCES AND BIOENGINEERING |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 01_fulltext.pdf | Attached File | 4.74 MB | Adobe PDF | View/Open |
| 04_abstract.pdf | 134.41 kB | Adobe PDF | View/Open | |
| 80_recommendation.pdf | 244.7 kB | Adobe PDF | View/Open |
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