Silk based tissue engineered strategies to repair damaged intervertebral disc

Abstract

Low back pain LBP is an important clinical and socio economic condition affecting the population indiscriminately across the globe Intervertebral disc IVD degeneration is the major cause of LBP The conventional therapies are only effective in symptomatic relief of pain without restoring the biomechanical function of native discs and are also associated with high expenditure of the treatment The emergence of tissue engineering technology provides a promising alternative strategy for the tr...