The role of aggregation of melamine and uric acid in kidney stone formation and its inhibition by small molecule inhibitors in solution and at the solid liquid interface a computational approach

Abstract

The thesis focuses on the aggregation property of small molecules related to various diseases that occur in humans and their inhibition by applying drugs with the use of molecular dynamics simulation in the solution phase and solid liquid interface Thus far the research findings are very enlightening In this thesis we have found an imperative conclusion that the aggregation propensity of uric acid is higher than uric acid melamine and melamine melamine interactions consequently a large clu